Cryptic Elliptic
9.27.2003
  getting back into things

Somehow it seems rude to say that I've had more important things to do lately, but, well, I have. For the most part, it's been NSF-grant-related stuff. If you're curious (and I don't know why you would be), I'm trying to choose between writing my grant proposal on some sort of pharmacogenetics experiment looking at secondary leukemias or on an experiment looking at the effects of CDK inhibition on histones. For right now, this means lots of pharmacogenetics reviews. There's some really interesting literature available on the legal and economic implications of pharmacogenetics; unfortunately, I'm not allowing myself to read things like that til I've worked through all the science. Maybe once I do get to read it I'll post something. I'm very attracted to pharmacogenetics as a research topic; the main disadvantage that it has over the histones experiment is that I'm more familiar with research techniques for the histones experiment. I'll get this all straightened out soon.

My G5 came, and it's gorgeous. Unfortunately, between orientation and NSF reading, I haven't been able to get it set up yet.

I went to REM's concert Friday night (in the company of Ed and Amanda). The concert itself was lovely (in particular, the dauntlessly bouncy Scott McCaughey warmed my heart); the weed-smoking aging hippie retreads, not so much. They played more of Reveal than I might have expected (All the Way to Reno, She Just Wants to Be, and Imitation of Life), but they played two of the songs I like best off of Lifes Rich Pageant (I Believe and Begin the Begin). The opener was Sparklehorse, of whom I had never heard. I don't know if they couldn't work with the sound system or what, but I couldn't understand a word of what they sang. I tried to write down the lyrics to one of their songs, and here's what I came up with:

Gonna get a little nookie (repeat four times)
Maude Gonne (repeat four times)
Gonna get a little chowder (repeat four times)

I assume these are wrong, as delightful as it would be to have a song about Yeats going to Boston (or whatever we can assume this to be about). I can't seem to find the real lyrics, though.

Today was occupied with shopping and watching a horrible movie. As far as the shopping goes, I can't see what the big fuss is over H&M. Looked like three floors of polyester crap to me, and it's not very cheap at that. Highlights (lowlights?) included a large shawl made out of Cookie Monster, the Itchiest Tube Top Ever (Lurex! Ouch!), the "Do Men Really Wear That?" "Maybe Just David Beckham" Metrosexual Top, and an entire line of clothes for hookers on skis. It's not really my sort of place, though; I'm decidedly untrendy, so cheap, trendy clothes that are only intended to last a season are pretty useless for me. After the shopping, there was ... Underworld. The movie, while it was pretty terrible (no movie that includes the line, "BITE HIM!!!!" and expects to be taken seriously can be any good), lent itself to all sorts of fun science discussion at dinner afterwards. I think the most significant conclusion that we came to was that the werewolves would be at a significantly higher risk of cancer than the normal population. Oh, speaking of fun science discussions, ask a biologist already. You slackers know who you are.

The redoubtable Emily has started a blog, which you should read. Emily makes a damn fine enchilada, and she has been known to be down with the sake pot.

From here on out, I expect I'll be back on the normal update schedule. Is that a good thing?  
9.19.2003
  catching up

I've been in Naperville for the past week or so, taking some time off before orientation. So far as I can tell, I've turned into a nerdy grandmother--all I've been doing is working on my NSF grant, knitting (a hobby I picked up two days ago), and walking the dog. Also, lots of MTV2.

I have also been reading the best book ever. Jessica Mitford's The American Way of Death Revisited (a revision of 1963's The American Way of Death is a scathing and hilarious critique of the funeral industry. I'll be able to speak more cogently about it when I've finished it, but I encourage you to read it.

Oh, and I've joined Will's evil dominion of comment-free blogs. I do think I like things better this way. If you do have any comments on anything, please feel free to email me. I imagine this will be more relevant when I'm posting actual content.  
9.09.2003
  on the mass

Kathleen blogs on the Latin Mass (and some basic etiquette). I used to think that I, too, preferred the Latin Mass. I still do on a purely aesthetic basis (don't see no lifeteen shit in a Latin Mass), and I do think that it's an experience that every Catholic should have. However, I'm a little too pro-Vatican II to really embrace Latin Mass--I think that the importance of the assembly that's stressed in the modern Mass (lay ministry, the position of the priest, recitation of more parts of the Mass by the assembly, and use of the vernacular) is Vatican II's most crucial legacy. It's the only regular reminder that most Catholics have of the catholic mission of Vatican II--to promulgate the call to holiness of all people. While we've lost the beauty of the Latin, I can't consider it anything but a necessary (though regrettable from an aesthetic standpoint) sacrifice.

And good God, people, of course you're not supposed to clap for liturgical music. Weren't you raised right?  
  aesthetic experiment

I have removed the comments (as well as an extraneous traffic-monitoring device) and am seeing how I like the looks of things. If you would like to make yourself heard (regarding the comments feature or anything else), please feel free to email me at srferrar at uchicago.edu.

Please feel especially free to email me if you have advice or information on the following topics: 
9.08.2003
  how to get into graduate school in biology--the visit

preface
In case you don't know, there are two kinds of visits--the interview weekend and the recruitment weekend. On an interview weekend, not everyone invited to visit will ultimately be accepted, so the weekend is your last chance to pitch yourself to the school. On a recruitment weekend, pretty much everyone who's invited will be accepted, and the school's trying to pitch itself to you. This isn't to say that you should behave differently at the two kinds of visits, though--the following advice applies for both sorts.

general tips for grad school visits:

 
  swamped

Apologies for my inactivity of late. I've been preoccupied--first, and most wholly, by my NSF application, secondly by mycoplasma infection of my poor cell stocks, and thirdly by rhinovirus infection of me. Not too much I can do about the latter two at this point, but if anyone has any helpful hints on how to get an NSF graduate fellowship, I'd love to hear them.

Oh, and does anyone want to go to the Mates of State concert on Thursday?  
9.01.2003
  how to get into graduate school in biology--the application

I was inspired by a recent post on Tacitus to tell you all how to get into bio grad school.

First of all, let's define what I mean by biology graduate school: a fully-funded doctoral program in biology. I understand that there are reasons for getting an MS in biology--you have more opportunities for advancement in a biotech firm, and you can do pretty well as a lab tech--but this isn't a path I'm going down, so I really don't know much about it. And I can't fathom why anyone would go to a graduate school that didn't waive their tuition and pay them a stipend. This is science--if it's a good program that wants you, it'll pay for you. Why would you go to a bad program, or a program that didn't want you? Better to wait a year and reapply.

The average application includes the following components (individual breakdowns follow): GPA/transcript, GRE scores (definitely general, possibly subject), a little bit about your research experience, faculty recommendations, and personal statement. I can't tell you which of these is most important--that really depends on the school, and anyway it seems that graduate schools tend to look at their applicants more holistically. A student with fair-to-middling GREs isn't going to be automatically rejected if they have a good GPA, impressive research experience, and glowing recommendations. Similarly, fantastic GREs can offset an unexceptional GPA (personally, I think this is pretty silly, as GREs are not a good predictor of graduate performance, but no one asked me). Don't worry too much if you have one weak area on your application so long as you can make it up elsewhere.

the transcript and the GPA
Obviously, your classes are important. I'm not going to go into the "three quarters of organic chem, two quarters of physics" ... rigamarole; a graduate program will generally tell you what courses it expects you to have taken. One thing I'd recommend (and this is especially important if your undergrad institution has pretty loose core requirements) is that you take a few biology courses that involve a lot of writing. It's not going to do you much good to have excellent research experience and plans if you can't write about them as a scientist. Furthermore, focus on courses that make you keep up with current research, especially ones that have you read a lot of journal articles. If you can't get enough experience reading articles in class, join or start a journal club. Reading journal articles isn't only a good way to learn about new developments in your field--it's also essential for learning techniques and experimental design. In graduate school, you need to know how research works. When you're designing an experiment, you need to know what techniques are relevant to answer your question, what exactly they can and cannot tell you, and how you're going to set up controls. A lot of undergraduate classes (and a lot of undergrad programs) do not focus at all on experimental design, to the great detriment of their students. Oh, and as far as GPA goes, don't be one of those grade-obsessed morons who takes the easiest classes he can find. Take the most challenging courses you can find. You needn't take ones that are hard because the instructor's bad, or that you find difficult because the topic isn't relevant to your interests, but it's important that you challenge yourself. A student with decent grades in a bunch of graduate classes will look better than a student with excellent grades in basic courses. Of course, a student with excellent grades in a bunch of graduate courses looks really good.

the GREs
You'll definitely have to take the general GREs, which, I assure you, are NOT THAT HARD. I tend to think that science students have an advantage over humanities students in the GRE--humanities students can forget math, while you're pretty unlikely to completely lose your verbal skills after English 101. So don't go wasting thousands of dollars on prep courses unless you know that you have some sort of testing problem. That said, it's still a good idea to look over a prep book, particularly one with sample tests. I used the Princeton Review's "Cracking the GRE" book--while the errors I found in the math problems annoyed me, the tests on the included CD-ROM were helpful in familiarizing me with the format of the test. If the math errata are going to bug you, too, Kaplan also has a book/CD-ROM combo to try. Note: the GRE has now dropped the analytical section (logic puzzles) in favor of a writing section, so devote your time accordingly.

As far as the subject exam goes, please make sure you need to take the exam before you go ahead and take it. Not all programs require it. Also, make sure you're taking the right test. The exam in Biochemistry, Cell, and Molecular Biology is newer than the regular Biology exam, so many grad schools aren't especially familiar with it. Also, it's supposed to be considerably harder--that is, a lower raw score corresponds to a higher percentile. My advice is to just take the Biology exam, which is pretty straightforward and easy, unless you need the other exam. And by all means, do NOT use the Best Test Preparation book (I'm linking to Amazon only so that you can see its cover and all of the horrible reviews). This book is purely awful--the tests are nothing like the actual GRE, and the book is filled with errors large and small (including the misidentification of molecular biology as microbiology and vice versa). DO NOT BUY THIS BOOK. The GRE tests provided by ETS are by far the best study guide.

the research
When I am a powerful department-mistress type, I shall not accept as a graduate student any student who elected not to do research as an undergraduate. If you are at a school where you can work as a research assistant, you absolutely must do so. It's a good idea to start working in a lab in your first (or early in your second) year as an undergraduate. Starting out as a dishwasher/media preparer is fine--it's a good way to get to know the people in the lab and see who you might want to work with. In the summer of your first year, try to work on a research project, whether you're a student assistant or an independent researcher. Once you gain enough experience in one lab, you can move to a different lab if your research interest changes (though staying at one lab is a rewarding experience as well). Also, it's important to talk about your research whenever you can--data club, lab meeting, formal presentations, boring random people on the street, whatever. You need to be able to speak intelligently about your research and to understand why your research topic is important.

While the main benefit of undergraduate research is that you're getting an early start on your career, it has lots of side benefits--you can throw together a B.A. really easily, and you're more attractive to graduate schools and grant-giving foundations. For some people, taking a year off after graduation to do research (and make money!) can be a good option--not only are you more attractive to grad schools, but it's easier for you to go on recruitment visits when you're not missing classes.

the recs
Faculty recommendations are fairly straightforward. Don't ask for a recommendation from a big-name professor who doesn't know you well. If you have done research, get a recommendation from your PI (or have a really good explanation for why you don't have one, because people will ask). If you do well in a class that's relevant to the field you want to study, ask the professor for a recommendation at the end of the class (this is where a service like Interfolio, which will hold onto your letters of recommendation for up to five years, is helpful). Basically, get recommendations from the people who are most familiar with your best work. Bear in mind that schools generally want no more than three or four recommendations--you can collect more if you're not sure which ones you want to use, but don't send the school more than it wants. Two final points of advice: I'm sure I don't even need to say this, but you always want to send a SEALED letter of recommendation (i.e. one that you aren't allowed to read). Unsealed letters are worthless. Also, make sure you give professors plenty of time to write your letters. At least two months is ideal.

the personal statement
Now, your GPA may be nothing remarkable, your GREs might be fair, you may not have a lot of research experience, or you may not know people who can write convincing letters of recommendation (okay, the last one's fairly unlikely). These are things you can't easily change. However, the personal statement is completely up to you, and it should be a positive addition to your application. Note: it's important not to confuse this personal statement with the kind required for med school and law school applications. Graduate admissions committees do not want to know about how your weaknesses have made you a stronger person or whatever. Also, you don't want to get overly creative with your personal statement--a friend of mine was told that the "originality" of her personal statement almost cost her admission to one of the programs she was considering.
Here's what you should cover:
If you're familiar with any professors on your undergraduate institution's graduate admissions committee, ask them to look over your personal statement--they'll have the best perspective on how it will be judged.

That's about all I have to say regarding the application, save this: make sure everything you hand in is well-proofread and on time unless you want to look like an unprofessional, inconsiderate slob.

Notes on "the visit" and "the decision" will follow.

Edited for typos and wayward parentheses, and also to direct your attention to some excellent advice at Pharyngula on why not to apply to grad school.  
I'm a cancer biology grad student at the University of Chicago. Born near Pittsburgh, grew up in Naperville, and I now live in Chicago. This is my blog, which appears to be mostly, though not exclusively, about biomedical things, education, Catholicism, Chicago, and complaining. Questions? Comments? Complaints? Email me at srferrar at uchicago.edu.
LINKS
I read, use, or support:
Crescat Sententia 
Crooked Timber
The Digital Dante Project
Emily's blog
Friendster
Gapers Block
Kathleen's blog
Lush
Matt's blog
Mildly Malevolent
Nature
OED
Pharyngula
PubMed
Reckless
Seminary Co-Op Bookstore
Sudeep's blog
Currently reading:

Assloads of research articles in an attempt to "catch up".


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